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TNMIN limits [message #57121] Sun, 02 December 2007 18:56 Go to previous message
biophys is currently offline  biophys
Messages: 68
Registered: July 2004
Member
Hi, Folks

I've been doing some maximum likelihood fitting with TNMIN. It's kind
of working fine except that I have to manually adjust the scaling of
my parameters to get the fitting going. Without proper scaling, it
seems that it will evaluate my function(s) outside of the parainfo
limits where it might be much more computational intensive to evaluate
or even undefined so that it doesn't converge or takes ridiculous
amount of time to converge. I am having a hard time to understand the
implementation details of TNMIN. Why does TNMIN insist evaluate my
function beyond my set limits? Is there a way to avoid this? If the
only way to avoid this is scaling, how to do automatic/adaptive
scaling to get it run in a for loop of a series of TNMIN fitting. I'd
appreciate any comments/hints!

Thanks!
BP
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